Tag Archives: preventive

20 to Know in Health Care: Clay Marsh

Captured  by Business First of Columbus

Why did you get into this profession?

I am fascinated by the complexity of our bodies and the foundational opportunity to improve people’s lives – quality and quantity. Moreover, I am fascinated by understanding the critical issues that determine human health and balance, which is the foundation for P4 (predictive, preventive, personalized and participatory) medicine. To realize P4 medicine, we need to create tools to promote health, create the environment or ecosystem that makes change easy and create the design to deliver a superior user experience. These principles of designing the tools, the world and the user experience is the secret to making health care transition from the doctor’s office and hospital to all parts of our life.

Is it as fulfilling as you thought it would be?

It is even more fulfilling that I originally planned. The ability to help people achieve beyond their expectations is tangible. I now appreciate the personal relationships, the ability to impact people’s lives and the extraordinarily important simple gifts of love, health, independence, family and purpose.

What’s the most exciting thing happening today in your industry?

Many exciting things are happening, including an expanded understanding of the genetic basis of human health and disease through research efforts, the rapid lowering of the cost of genetic sequencing, new precision drugs for a number of diseases based on genetic targets, including cancer, heart disease and neurological disease, are few examples of precision medicine. While these advances are exciting, they largely are dealing with sickness. Tomorrow, we want to move medicine from clinical disease to health and understand how we predict the risk of developing these problems, prevent these problems from occurring, personalize the approach and have true participation from our communities which is the basis of P4 Medicine.

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Boston Medical Center’s Pantry-by-Prescription Program Recognized with National Award

Captured by The Boston Globe

Food is medicine. That’s the basic premise behind the Preventive Food Pantry at Boston Medical Center.

Doctors at the hospital can write prescriptions for patients to visit the pantry twice a month. Just as for insulin or blood pressure medications, the prescription becomes part of the patient’s medical record, allowing them to return to the pantry to stock up on fresh vegetables and canned goods. A chef provides lessons in a demonstration kitchen about how to prepare healthy food.

The program, which assisted more than 80,000 people last year, is being recognized with the James W. Varnum National Quality Health Care Award from Dartmouth-Hitchcock, named for the health system’s long-time president.

The pantry is supported by donations and is only available to people who have been referred by their doctor. Many of the patients served have diabetes, unhealthy weight, or food allergies directly affected by eating habits.

“The creative approach taken by BMC in making nutritious food and education readily available to patients is a terrific example of providing value at relatively low cost, putting patients on the road to a healthier lifestyle and helping prevent costlier care later in their lives,” said Dr. George T. Blike, Dartmouth-Hitchcock’s chief quality officer.

The pantry is one of several programs at the Boston hospital focused on prescribing services that go beyond traditional medicine. With Health Leads , a program founded in the Boston Medical Center pediatrics department and now a nonprofit working in six cities, doctors write prescriptions for a family to visit volunteers who can connect them to home heating assistance, for example.

The award is given every two years and will be presented Nov. 27 at Dartmouth-Hitchcock Medical Center in Lebanon. A video about the program will be presented to Boston Medical Center, as part of the award, to help publicize it.

Ohio State’s P4 Medicine Update, May 30, 2012

Captured by Sherri Kirk

Lee Hood’s P4 Medicine Institute Gets New Partner, PeaceHealth

Captured by Xconomy.com

Leroy Hood‘s fledgling institute for personalized medicine struck its first big partnership with an academic medical center two years ago. Now it’s branching out to include some Northwest hospitals that are philosophically a lot closer to the community than to the academy. The P4 Medicine institute, a nonprofit inside the Seattle-based Institute for Systems Biology, is announcing today it has formed an alliance with PeaceHealth, a nonprofit Catholic health system with 17,000 employees at community medical locations around Washington, Oregon & Alaska. PeaceHealth is the first community health system to enter the P4 medicine network, after Ohio State University became the first academic medical center to join two years ago. By working with the Institute for Systems Biology and Ohio State, PeaceHealth is seeking to put itself on the edge of Hood’s “P4″ vision, shorthand for predictive, preventive, personalized and participatory medicine.

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Washington’s PeaceHealth Joins ISB-led Personalized Medicine Initiative

Captured by GenomeWeb

PeaceHealth, a Washington state-based non-profit health system, has partnered with the P4 Medicine institute, or P4Mi, a non-profit consortium focused on applying personalized medicine in the clinic, the partners announced today.

PeaceHealth said that its partnership with P4 Medicine, which was launched in 2010 by the Institute for Systems Biology and The Ohio State University, will ultimately provide its network of medical centers in Washington, Alaska, and Oregon with new genome-based predictive and diagnostic tools.

The non-profit said that it will work with P4Mi leaders to identify pilot projects that will be launched over the next two years in its medical practices and communities.

P4Mi is centered around the vision of advancing what Leroy Hood, ISB co-founder and president and chairman of P4Mi’s board of directors, calls P4 medicine — healthcare that is predictive, preventive, personalized, and participatory.

“PeaceHealth will help us integrate emerging biologic science into community-based care models, and make innovations in wellness and health accessible to whole communities,” Hood said in a statement.

“Over time, we hope to take rapidly emerging P4Mi health and wellness innovations and integrate them into everyday interactions between PeaceHealth providers and their patients to better predict, prevent, and treat disease,” added Peter Adler, PeaceHealth’s senior VP for strategy, innovation, and development.

The partnership agreement makes PeaceHealth a founding community health partner of P4Mi, along with OSU’s Center for Personalized Health at the Wexner Medical Center.

Seeking Clues to Heart Risk in a Patient’s Family Tree

The Wall Street Journal

Doctors often gloss over a key question for assessing a person’s risk for coronary heart disease, according to a new study: What is the patient’s family history of cardiovascular illness?

The study suggests some doctors may not be capturing the full extent of many patients’ chances of developing heart disease. Detailed family information could help doctors better predict who is at risk and more accurately target patients for preventive care that may help avert the disease altogether, according to the study, due to be published Tuesday in the Annals of Internal Medicine. Routinely tracking family history sharply boosted the number of people in the study considered at high risk for heart disease.

A widely used scorecard for measuring heart risk, the Framingham Risk Score, fails to take family history directly into account. And while many doctors currently collect some information about the health of their patients’ families, the data often lack the detail to be clinically useful for assessing risk and prescribing care.

“Family history remains one of the most important predictors of an event for an individual,” says Donna Arnett, a genetic epidemiologist at the University of Alabama at Birmingham and president-elect of the American Heart Association. Still, “most of the family history that we’re collecting is just the presence or the absence of heart disease, not the age of onset or the type of disease,” says Dr. Arnett, who wasn’t involved in the latest research.

Guidelines for heart-risk screening, issued by the heart association in late 2010, encouraged doctors to take family histories into account. Doctors sometimes make judgment calls to treat people as high risk because of family history, even if it isn’t part of the patient’s risk score.

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Vitamin E Tocotrienol Supplement Delays Progression of Advanced Liver Disease

Captured by Sherri Kirk

COLUMBUS, Ohio – New research conducted at The Ohio State University’s Wexner Medical Center suggests an alternate form of natural vitamin E delays the progression of disease in patients awaiting liver transplantation, the only definitive therapy that reduces a patient’s morbidity, mortality and improves their quality of life. The study shows, for the first time, successful delivery of the vitamin – administered orally – to vital human organs such as the brain, heart, liver, skin and fatty tissue.

Researchers at Ohio State’s Wexner Medical Center initially sought to measure levels of vitamin E tocopherol (TCP) and vitamin E tocotrienol (TE) in tissue and vital organs of patients with end stage liver disease. The data displayed a significant increase in TE levels in the bloodstream and tissue of study participants who received daily oral supplements of TE.

“This work is the first to show oral supplements of tocotrienol are being transported to the vital organs of patients,” says Chandan K. Sen, associate dean for translational and applied research in The Ohio State University College of Medicine. “This is exciting evidence for patients at high risk for stroke because our previous work identified low levels of TE to be protective against stroke-induced damage to the brain. Findings of this current research are equally excited for patients on the liver transplant list as it increases their chances of receiving a new liver, and therefore survival.”

Earlier research published by Dr. Sen and colleagues at Ohio State’s Medical Center proved tocotrienol a safe and neuroprotective nutrient, which minimizes stroke-related damage to the brain. “We also showed in previous studies that TE can be part of a regular diet and keeps the brain enriched and better prepared to defend itself,” added Sen, also vice chair for research in Ohio State’s Department of Surgery.

For this recent study, published in the February issue of Journal of Nutrition, researchers studied blood and tissue samples from 80 participants. One cohort involved healthy patients who received oral TE or TCP supplements. Vitamin E levels found in tissue were measured in healthy participants after 12 weeks of receiving oral supplementation. Healthy adult participants were selected for this study because they could receive oral supplements for a designated period of time, whereas the other cohort was bound by surgery schedules.

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